The pancreas is the major organ controlling blood sugar. Sugar (glucose) in the blood is a major source of energy. The correct amount of sugar in the blood produces health. Any amounts, greater or less, in the extreme, tend to create disease via too much (hyperglycemia) or too little (hypoglycemia) sugar in the blood. Hyperglycemia, hypoglycemia and diabetes are three ?blood sugar? diseases associated with the pancreas.