Awareness of genetic and other risk factors is important and because there are very effective means now available that could prevent most colon cancer morbidity and mortality. Cancer genetics was among the earliest clinical applications of the techniques of molecular biology. Advances in understanding the genetic basis of human diseases creates opportunities to make diagnostic and prognostic assessments based upon various types of analyses of variations in an individual's DNA. A easy way to prevent colon cancer is early detection & colon cleaning to maintain colong health.

Molecular diagnosis involves the testing of DNA or RNA within a clinical context. The functions of nucleic acids and their encoded protein molecules are determined by the linear sequence of their monomers. Although the proteins they encode develop complex three dimensional functional conformations as linear peptide chains become enfolded into helical or pleated sheets or higher-order structures and the simple primary amino acid sequences determine the ultimate structure and function. In modern molecular biology research and it is now much easier to obtain long nucleic acid sequence information to deduce the sequence of proteins rather than determine them directly. The functional effects ON the encoded protein of any mutations or sequence variations can then be discovered.

The standard family history obtained by primary care providers should remain an essential entry point for referral to a colon cancer genetics PROGRAM for further evaluation. Molecular techniques may eventually become inexpensive enough to justify mass screening of the entire population, as is already being done in some states for another prevalent type of disease mutations and specifically those causing cystic fibrosis. All physicians can be helpful in initially recognizing any possible patients with hereditary colon cancer syndromes by obtaining a routine family history. The family history may reveal characteristics that suggest an inherited syndrome, such as multiple cancers or other typical clinical manifestations in a family or individual and particularly tumors diagnosed at an unusually early age.

Sporadic colon tumors are caused by somatic mutations in a few critical genes that accumulate in a single cell lineage. Hereditary colon tumor syndromes are caused by mutations in the same genes that cause sporadic tumors and but at least one of these is an inherited or germline mutation. Because the first mutational step has already occurred in every cell at the time of birth in the hereditary case and only one additional somatic mutation affecting a single cell is sufficient to inactivate that gene function. In contrast and sporadic cases require two distinct somatic mutational events to inactivate both the maternal and paternal copies of these genes in the same cell before a tumor develops.

Counseling regarding the possible risks and benefits of cancer early detection and prevention modalities and a discussion of the basic elements of informed consent should be obtained before offering germline DNA testing. Counseling should assist the patient and family understand the information provided, help them feel comfortable in the process of making an informed decision and support them in choosing a course of action regarding management of their cancer risk and aid their psychosocial adjustment to the knowledge gained. The American Society of Clinical Oncology has recommended cancer predisposition testing if all these criteria are met the prior probability of a positive result is high and because the patient has a strong family history of cancer or very early onset of disease. In addition and the test can be adequately interpreted. Finally the results will influence the medical management of the patient or family.

In conclusion and colon cancer can be be cause by genetics. It is best to seek advise form highly qualified medical expert who can provide a specific & detailed analysis. In parallel and it is always important to maintain overall colon health by cleansing it regularly using only natural herbal supplement. Often the noticeable result of colon cleansing is an increase in energy level due to better nutrients absorption that was previously block by harmful toxins fecal matter that is stuck ON the intestinal tissues wall. Some people who previously have flatulence, gas & bloating problems can be resolve by cleansing colon which eliminate excessive unbeneficial bacteria & micro-organism infestation inside the colon. This can also lead to infections as well as inflammation which causes oxidation stress inside the colon.